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Search Results for " acc, acetyl coenzyme a carboxylase "

11

Compounds

Cat No. Product Name Synonyms Targets
T3510 Olumacostat Glasaretil Acetyl-CoA Carboxylase
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
TQ0243 ND-646 Acetyl-CoA Carboxylase
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)
T7163 PF-05175157 Acetyl-CoA Carboxylase
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively
T5046 Haloxyfop Haloxyfop Acid,(±)-Haloxyfop Others , Acetyl-CoA Carboxylase
(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.
T3988 TOFA MDL14514,RMI14514 Acetyl-CoA Carboxylase
TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
T14991 CMS-121 CMS121 Acetyl-CoA Carboxylase
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...
T1889 CP-640186 CP 640186 Acetyl-CoA Carboxylase
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
T3622 CP-640186 hydrochloride CP 640186 HCl Acetyl-CoA Carboxylase
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...
T7184 Firsocostat ND-630,NDI-010976,GS-0976 Acetyl-CoA Carboxylase
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
T8754 CPD2028 Others
CPD2028 is an intermediate of ND630, a potent acetyl coenzyme A carboxylase (ACC) inhibitor.
T73054 Moiramide B Acetyl-CoA Carboxylase , Antibiotic
Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria.
TargetMol