11
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3510 | Olumacostat Glasaretil | Acetyl-CoA Carboxylase | |
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris. | |||
TQ0243 | ND-646 | Acetyl-CoA Carboxylase | |
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively) | |||
T7163 | PF-05175157 | Acetyl-CoA Carboxylase | |
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively | |||
T5046 | Haloxyfop | Haloxyfop Acid,(±)-Haloxyfop | Others , Acetyl-CoA Carboxylase |
(±)-Haloxyfop (Haloxyfop Acid) is a herbicide. | |||
T3988 | TOFA | MDL14514,RMI14514 | Acetyl-CoA Carboxylase |
TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). | |||
T14991 | CMS-121 | CMS121 | Acetyl-CoA Carboxylase |
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect... | |||
T1889 | CP-640186 | CP 640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | |||
T3622 | CP-640186 hydrochloride | CP 640186 HCl | Acetyl-CoA Carboxylase |
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit... | |||
T7184 | Firsocostat | ND-630,NDI-010976,GS-0976 | Acetyl-CoA Carboxylase |
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively) | |||
T8754 | CPD2028 | Others | |
CPD2028 is an intermediate of ND630, a potent acetyl coenzyme A carboxylase (ACC) inhibitor. | |||
T73054 | Moiramide B | Acetyl-CoA Carboxylase , Antibiotic | |
Moiramide B is a potent acetyl coenzyme A carboxylase (ACC) inhibitor (IC50:6 nM) with antimicrobial activity, strongly inhibiting Gram-positive bacteria but weakly inhibiting Gram-negative bacteria. |